Perfluorooctanoic acid (PFOA), perfluorooctane sulfonate (PFOS), and other per- and polyfluoroalkyl substances (PFAS) cause many public health and environmental issues. PFOA and PFAS are bioaccumulative and water-soluble. They are widely used within many industries, and as a result, can now be found in the groundwater, rivers, and lakes. Exposure to PFAS can cause negative health effects, such as immunotoxicity, neurotoxicity, endocrine-disrupting effects, and developmental effects. Due to the high C-F bond strength in PFAS, conventional and even advanced oxidation treatments do not effectively break them down. Some reduction methods have shown success in breaking down PFAS compounds. Nanoscale zero-valent iron (nZVI) can effectively adsorb and reduce PFOA. However, it can be toxic to the environment, and often experiences reduced activity due to agglomeration.Dr. Dionysiou at UC, Dr. Mallik Nadagouda at US EPA and their co-inventors have responded to these challenges and developed a unique catalyst and resin combination which has been shown to remove almost all (~98%) of PFOA (1 mg L−1) within a reaction time of 240 minutes. This method makes use of both oxidative and reductive species, leading to very effective degradation of PFOA.